neural development

By Targets:	Endogenous Metabolite (3) Isotope-Labeled Compounds (1)
By Research Areas:	Cancer (1) Neurological Disease (4)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0921

(±)-1,2-Propanediol 1 Publications Verification 1,2-(RS)-Propanediol; 1,2-Propylene glycol; Propylene glycol	Endogenous Metabolite	Neurological Disease
(±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .

HY-16637D

Folic acid disodium Vitamin B9 disodium; Vitamin M disodium	Endogenous Metabolite	Others Neurological Disease Cancer
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 ⁵ g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .

HY-134104

C20-Sphingosine

D-erythro-Sphingosine-C20
Others Neurological Disease

C20-Sphingosine is a long-chain base (LCB) that can be used in the study of neural development .

C20-Sphingosine D-erythro-Sphingosine-C20	Others	Neurological Disease
C20-Sphingosine is a long-chain base (LCB) that can be used in the study of neural development .

HY-Y0921S3

(±)-1,2-Propanediol-13C3 1,2-(RS)-Propanediol-¹³C₃; 1,2-Propylene glycol-¹³C₃; Propylene glycol-¹³C₃	Endogenous Metabolite Isotope-Labeled Compounds	Neurological Disease
(±)-1,2-Propanediol- ¹³C₃ is ¹³C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .

Cat. No.	Product Name

HY-L013

Neuronal Signaling Compound Library	2,572 compounds
Neuronal Signaling is involved in the regulation of the mechanisms of the central nervous system (CNS) such as its structure, function, genetics and physiology as well as how this can be applied to understand diseases of the nervous system. Every information processing system in the CNS is composed of neurons and glia, neurons have evolved unique capabilities for intracellular signaling (communication within the cell) and intercellular signaling (communication between cells). G protein-coupled receptors (GPCRs), including 5-HT receptor, histamine receptor, opioid receptor, etc. are the largest class of sensory proteins and are important therapeutic targets in Neuronal Signaling. Besides, Notch signaling, such as β- and γ-secretase, also plays multiple roles in the development of the CNS including regulating neural stem cell (NSC) proliferation, survival, self-renewal and differentiation. GPCR dysfunction caused by receptor mutations and environmental challenges contributes to many neurological diseases. Notch signaling in neurons, glia, and NSCs is also involved in pathological changes that occur in disorders such as stroke, Alzheimer's disease and CNS tumors. Thus, targeting Neuronal Signaling, such as notch signaling and GPCRs, can be used as therapeutic interventions for several different CNS disorders. MCE designs a unique collection of 2,572 Neuronal Signaling-related compounds that act as a useful tool for the research of neuronal regulation and neuronal diseases.

Neuronal Signaling Compound Library

2,572 compounds

Neuronal Signaling is involved in the regulation of the mechanisms of the central nervous system (CNS) such as its structure, function, genetics and physiology as well as how this can be applied to understand diseases of the nervous system. Every information processing system in the CNS is composed of neurons and glia, neurons have evolved unique capabilities for intracellular signaling (communication within the cell) and intercellular signaling (communication between cells). G protein-coupled receptors (GPCRs), including 5-HT receptor, histamine receptor, opioid receptor, etc. are the largest class of sensory proteins and are important therapeutic targets in Neuronal Signaling. Besides, Notch signaling, such as β- and γ-secretase, also plays multiple roles in the development of the CNS including regulating neural stem cell (NSC) proliferation, survival, self-renewal and differentiation. GPCR dysfunction caused by receptor mutations and environmental challenges contributes to many neurological diseases. Notch signaling in neurons, glia, and NSCs is also involved in pathological changes that occur in disorders such as stroke, Alzheimer's disease and CNS tumors. Thus, targeting Neuronal Signaling, such as notch signaling and GPCRs, can be used as therapeutic interventions for several different CNS disorders.

MCE designs a unique collection of 2,572 Neuronal Signaling-related compounds that act as a useful tool for the research of neuronal regulation and neuronal diseases.

Cat. No.	Product Name	Type

HY-Y0921

(±)-1,2-Propanediol 1 Publications Verification 1,2-(RS)-Propanediol; 1,2-Propylene glycol; Propylene glycol	Co-solvents
(±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0921

(±)-1,2-Propanediol 1 Publications Verification 1,2-(RS)-Propanediol; 1,2-Propylene glycol; Propylene glycol	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease markers Other Diseases Endogenous metabolite Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite
(±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .

HY-134104

C20-Sphingosine D-erythro-Sphingosine-C20	Structural Classification Natural Products Source classification Endogenous metabolite	Others
C20-Sphingosine is a long-chain base (LCB) that can be used in the study of neural development .

Cat. No.	Product Name	Chemical Structure

HY-Y0921S3

(±)-1,2-Propanediol-13C3
(±)-1,2-Propanediol- ¹³C₃ is ¹³C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .

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neural development

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products